REFERENCIAS BIBLIOGRÁFICAS

  • Sinclair D, LaPlante M. Lifespan why we age and why we don ́t have to. New York: Atria; 2019.Sinclair D, LaPlante M. Lifespan why we age and why we don ́t have to. New York: Atria; 2019.
  • López-Otín C, Blasco M, Partridge L, Serrano M, Kroemer G. The hallmarks of aging. Cell.2013; 153:1194-1217.
  • Srivastava S. The mitochondrial basis of aging. Genes. 2017; 8:398.
  • Giordani C, Silvestrini A, Giuliani A, Olivieri F, Rippo M. MicroRNAs as Factors inBidirectional Crosstalk Between Mitochondria and the Nucleus During Cellular Senescence. FrontPhysiol. 2021; 12:734976.
  • Know L. Mitochondria and the Future of Medicine: The key to understanding disease, chronicillness, aging, and life. 2a ed. Vermont: Chelsea Green Publishing; 2018.
  • Alarcón-Aguilar A, Maycotte-González P, Cortés-Hernández P, López Diazguerrero N,Königsberg M. Dinámica mitocondrial en enfermedades neurodegenerativas. Gac Méd Mex. 2019;155.
  • Popoy L. Mitochondrial biogenesis: an update. J Cell Mol Med. 2020; 24: 4892– 4899.
  • Wenz T.. Regulation of mitochondrial biogenesis and PGC1α under cellular stress.Mitochondrion. 2013; 13: 134-42.
  • Milone M, Benarroch E. Mitochondrial dynamics: general concepts and clinical implications.Neurology. 2012; 78:1612-9.
  • Bárcena C, Mayoral P, Quirós P. Mitohormesis, an Antiaging Paradigm. Int Rea Cell Mol Biol.2018; 340:35-77.
  • Cho J, Hui Jae, Walker D. The role of mitochondria in Drosophila Aging. Exp Gerontol. 2011;46:331-334.
  • Tatar M, Bartke A, Antebi A. The endocrine regulation of aging by insulin-like signals.Science. 2003; 299: 1346-51.
  • Longo V, Fontana L. Calorie restriction and cancer prevention: metabolic and molecularmechanisms. Trends Pharmacol Sci. 2010; 31:89-98.
  • Colman R, Anderson R, Johnson S, Kastman E, Kosmatka K, Beasley T, et al. Caloricrestriction delays disease onset and mortality in rhesus monkeys. Science. 2009; 325:201-4.
  • Longo V, Mattson M. Fasting: Molecular mecanismos and Clinical Applications. Cell Metab.2014; 19:181-192.
  • Longo V, Antebi A, Bartke A, Barzilai Nir, Brown-Borg H, Caruso C, Curiel, et al.Interventions to Slow Aging in Humans: Are We Ready?. Aging Cell. 2015; 14:497-510.
  • Srivastava S, Baxa U, Niu G, Chen X, Veces R. A ketogenic diet increases brown adiposetissue mitochondrial proteins and UCP1 levels in mice. IUBMB Life. 2013; 65:58-66.
  • Mercken E, Crosby S, Lamming D, JeBailey L, Krzysik-Walker S, Villareal D, et al. Calorierestriction in humans inhibits the P13K/AKT pathway and induces a younger transcription profiles.Aging Cell. 2013; 12:645-51.
  • Memme J, Erlich A, Phukan G, Hood D. Exercise and mitochondrial health. J Physiol. 2021;599: 803-817.
  • Rajman L, Chwalek K, Sinclair D. Therapeutic potential of NAD boosting molecules: the invivo evidence. Cell Metab. 2018; 27:529-547.
  • Manzar H, Abdulhussein D, Gap T, Cordeiro M. Cellular Consequences of Coenzyme Q10Deficiency in Neurodegeneration of the Retina and Brain. Int J Mol Sci. 2020; 21:9299.
  • Baur J, Sinclair D. Therapeutic potential of resveratrol: the in vivo evidence. Nat Rev DrugDiscov. 2006; 5: 493-506.
  • Melhuish L, Brown G, Gonçalves V, Kennedy J. Melatonin ́s neuroprotective role inmitocondria and its potential as a biomarker in aging, cogniction and psychiatric disorders. TranslPsychiatry. 2021; 11:339.
  • Martin-Montalvo A, Mercken E, Mitchell S, Palacios H, Mote P, Scheibye- Knudsen M, et al.Metformin improvise healthspan and lifespan in mice. Nat Commun. 2013; 4:2192.